The long‐term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status
Identifieur interne : 002697 ( Main/Exploration ); précédent : 002696; suivant : 002698The long‐term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status
Auteurs : Jenny C. Ngai [République populaire de Chine] ; Fanny W. Ko [République populaire de Chine] ; Susanna S. Ng [République populaire de Chine] ; Kin-Wang To [République populaire de Chine] ; Mabel Tong [République populaire de Chine] ; David S. Hui [République populaire de Chine]Source :
- Respirology [ 1323-7799 ] ; 2010-04.
Abstract
Background and objective: Severe acute respiratory syndrome (SARS) emerged in 2003 and its long‐term sequelae remain largely unclear. This study examined the long‐term outcome of pulmonary function, exercise capacity, health and work status among SARS survivors. Methods: A prospective cohort study of SARS patients at the Prince of Wales Hospital, Hong Kong was conducted, with serial assessments of lung function, 6MWD and 36 item Short Form General Health Survey at 3, 6, 12, 18 and 24 months after disease onset. The work status was also recorded. Results: Serial assessments were completed by 55 of the 123 (39.9%) subjects, of whom 27 were health‐care workers (HCW). The mean age of the group was 44.4 (SD 13.2) years and 19 (34.5%) were males. At 24 months, 10 (18.2%), 9 (16.4%), 6 (10.9%) and 29 (52.7%) subjects had FEV1, FVC, TLC and DLCO < 80% of predicted values, respectively. The mean (SD) 6MWD increased significantly from 439.0 (89.1) m at 3 months to 460.1 (102.8) m at 6 months (P 0.016) and became steady after 6 months. However, 6MWD and 36 item Short Form General Health Survey scores were lower than the normal population throughout the study. Moreover, 29.6% of HCW and 7.1% of non‐HCW had not returned to work 2 years after illness onset. Conclusions: This 2‐year study of a selected population of SARS survivors, showed significant impairment of DLCO, exercise capacity and health status persisted, with a more marked adverse impact among HCW.
This study consists of serial assessments of lung function, 6MWD, 36 item Short Form General Health Survey and work status of survivors of severe acute respiratory syndrome (SARS) over 24 months. There was persistent and significant impairment of DLCO, exercise capacity and health status, with more marked adverse impact among the health‐care workers.
Url:
DOI: 10.1111/j.1440-1843.2010.01720.x
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Istex, to step Corpus: 000B81
- to stream Istex, to step Curation: 000B81
- to stream Istex, to step Checkpoint: 000950
- to stream Main, to step Merge: 002736
- to stream Main, to step Curation: 002697
Le document en format XML
<record><TEI wicri:istexFullTextTei="biblStruct"><teiHeader><fileDesc><titleStmt><title xml:lang="en">The long‐term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status</title><author><name sortKey="Ngai, Jenny C" sort="Ngai, Jenny C" uniqKey="Ngai J" first="Jenny C." last="Ngai">Jenny C. Ngai</name></author><author><name sortKey="Ko, Fanny W" sort="Ko, Fanny W" uniqKey="Ko F" first="Fanny W." last="Ko">Fanny W. Ko</name></author><author><name sortKey="Ng, Susanna S" sort="Ng, Susanna S" uniqKey="Ng S" first="Susanna S." last="Ng">Susanna S. Ng</name></author><author><name sortKey="To, Kin Ang" sort="To, Kin Ang" uniqKey="To K" first="Kin-Wang" last="To">Kin-Wang To</name></author><author><name sortKey="Tong, Mabel" sort="Tong, Mabel" uniqKey="Tong M" first="Mabel" last="Tong">Mabel Tong</name></author><author><name sortKey="Hui, David S" sort="Hui, David S" uniqKey="Hui D" first="David S." last="Hui">David S. Hui</name></author></titleStmt><publicationStmt><idno type="wicri:source">ISTEX</idno><idno type="RBID">ISTEX:96911BD921344EBB74172A5267CB1A76B1868AE5</idno><date when="2010" year="2010">2010</date><idno type="doi">10.1111/j.1440-1843.2010.01720.x</idno><idno type="url">https://api.istex.fr/ark:/67375/WNG-K6K4Z7N6-H/fulltext.pdf</idno><idno type="wicri:Area/Istex/Corpus">000B81</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Corpus" wicri:corpus="ISTEX">000B81</idno><idno type="wicri:Area/Istex/Curation">000B81</idno><idno type="wicri:Area/Istex/Checkpoint">000950</idno><idno type="wicri:explorRef" wicri:stream="Istex" wicri:step="Checkpoint">000950</idno><idno type="wicri:doubleKey">1323-7799:2010:Ngai J:the:long:term</idno><idno type="wicri:Area/Main/Merge">002736</idno><idno type="wicri:Area/Main/Curation">002697</idno><idno type="wicri:Area/Main/Exploration">002697</idno></publicationStmt><sourceDesc><biblStruct><analytic><title level="a" type="main">The long‐term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status</title><author><name sortKey="Ngai, Jenny C" sort="Ngai, Jenny C" uniqKey="Ngai J" first="Jenny C." last="Ngai">Jenny C. Ngai</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Ko, Fanny W" sort="Ko, Fanny W" uniqKey="Ko F" first="Fanny W." last="Ko">Fanny W. Ko</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Ng, Susanna S" sort="Ng, Susanna S" uniqKey="Ng S" first="Susanna S." last="Ng">Susanna S. Ng</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="To, Kin Ang" sort="To, Kin Ang" uniqKey="To K" first="Kin-Wang" last="To">Kin-Wang To</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Tong, Mabel" sort="Tong, Mabel" uniqKey="Tong M" first="Mabel" last="Tong">Mabel Tong</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author><author><name sortKey="Hui, David S" sort="Hui, David S" uniqKey="Hui D" first="David S." last="Hui">David S. Hui</name><affiliation wicri:level="4"><country xml:lang="fr">République populaire de Chine</country><wicri:regionArea>Department of Medicine & Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong</wicri:regionArea><orgName type="university">Université chinoise de Hong Kong</orgName><placeName><settlement type="city">Sha Tin</settlement></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Respirology</title><title level="j" type="alt">RESPIROLOGY</title><idno type="ISSN">1323-7799</idno><idno type="eISSN">1440-1843</idno><imprint><biblScope unit="vol">15</biblScope><biblScope unit="issue">3</biblScope><biblScope unit="page" from="543">543</biblScope><biblScope unit="page" to="550">550</biblScope><biblScope unit="page-count">8</biblScope><publisher>Blackwell Publishing Asia</publisher><pubPlace>Melbourne, Australia</pubPlace><date type="published" when="2010-04">2010-04</date></imprint><idno type="ISSN">1323-7799</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">1323-7799</idno></seriesStmt></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Background and objective: Severe acute respiratory syndrome (SARS) emerged in 2003 and its long‐term sequelae remain largely unclear. This study examined the long‐term outcome of pulmonary function, exercise capacity, health and work status among SARS survivors. Methods: A prospective cohort study of SARS patients at the Prince of Wales Hospital, Hong Kong was conducted, with serial assessments of lung function, 6MWD and 36 item Short Form General Health Survey at 3, 6, 12, 18 and 24 months after disease onset. The work status was also recorded. Results: Serial assessments were completed by 55 of the 123 (39.9%) subjects, of whom 27 were health‐care workers (HCW). The mean age of the group was 44.4 (SD 13.2) years and 19 (34.5%) were males. At 24 months, 10 (18.2%), 9 (16.4%), 6 (10.9%) and 29 (52.7%) subjects had FEV1, FVC, TLC and DLCO < 80% of predicted values, respectively. The mean (SD) 6MWD increased significantly from 439.0 (89.1) m at 3 months to 460.1 (102.8) m at 6 months (P 0.016) and became steady after 6 months. However, 6MWD and 36 item Short Form General Health Survey scores were lower than the normal population throughout the study. Moreover, 29.6% of HCW and 7.1% of non‐HCW had not returned to work 2 years after illness onset. Conclusions: This 2‐year study of a selected population of SARS survivors, showed significant impairment of DLCO, exercise capacity and health status persisted, with a more marked adverse impact among HCW.</div><div type="abstract">This study consists of serial assessments of lung function, 6MWD, 36 item Short Form General Health Survey and work status of survivors of severe acute respiratory syndrome (SARS) over 24 months. There was persistent and significant impairment of DLCO, exercise capacity and health status, with more marked adverse impact among the health‐care workers.</div></front></TEI><affiliations><list><country><li>République populaire de Chine</li></country><settlement><li>Sha Tin</li></settlement><orgName><li>Université chinoise de Hong Kong</li></orgName></list><tree><country name="République populaire de Chine"><noRegion><name sortKey="Ngai, Jenny C" sort="Ngai, Jenny C" uniqKey="Ngai J" first="Jenny C." last="Ngai">Jenny C. Ngai</name></noRegion><name sortKey="Hui, David S" sort="Hui, David S" uniqKey="Hui D" first="David S." last="Hui">David S. Hui</name><name sortKey="Ko, Fanny W" sort="Ko, Fanny W" uniqKey="Ko F" first="Fanny W." last="Ko">Fanny W. Ko</name><name sortKey="Ng, Susanna S" sort="Ng, Susanna S" uniqKey="Ng S" first="Susanna S." last="Ng">Susanna S. Ng</name><name sortKey="To, Kin Ang" sort="To, Kin Ang" uniqKey="To K" first="Kin-Wang" last="To">Kin-Wang To</name><name sortKey="Tong, Mabel" sort="Tong, Mabel" uniqKey="Tong M" first="Mabel" last="Tong">Mabel Tong</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Sante/explor/SrasV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002697 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002697 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Sante
|area= SrasV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= ISTEX:96911BD921344EBB74172A5267CB1A76B1868AE5
|texte= The long‐term impact of severe acute respiratory syndrome on pulmonary function, exercise capacity and health status
}}
| This area was generated with Dilib version V0.6.33. |  |